Research · 1 November 2026

Claude Sonnet 5 autonomously selects gene therapy and performs mouse brain surgery

Claude Sonnet 5 chose a gene therapy, target region, and injection parameters for an epileptic mouse, executed the surgery with a motorized device, and halted when a safety restriction triggered, refusing to bypass it.

Why it matters

Plan for fallback mechanisms; the agent’s self‑stop under safety limits shows the need for human‑override pathways.

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